Upgrade Exchange 2016 to the latest cumulative update

Exchange Server 2016 will also follow the same Quarterly release pattern.

CU 1 has been released in March 14 this year.

with this update Microsoft now ships setup in ISO file, once think i wonder about is when i first installed the exchange server in my lab the Exchange Setup exe file was about 2 GB and this ISO file size about 6 GB which is 3 time higher then the original setup exe.

Well you have already install Exchange 2016 already installed in your production and looking to download the CU you can download the same from here.

https://www.microsoft.com/en-us/download/details.aspx?id=51497

Warning: After you upgrade Exchange 2016 to a newer cumulative update, you can't uninstall the new version to revert to the previous version. If you uninstall the new version, you remove Exchange from the server.

You can install the cumulative update for Exchange 2016 by using either the Setup wizard or via unattended mode. For specific instructions, see the following topics:
NOTE: Exchange 2016 cumulative updates include all the changes from previous updates and are full builds of the product. You don't have to install the previous cumulative updates to get the latest features.  

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